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Red Flag Radiculopathy, Pancoast Tumors and Thoracic Outlet Pathology

Episode
4 of 4
Published
Nov 28th, 2025
Run time
14m 54s
Topic
Recognising Red Flag Pathologies in the Neck and Upper Quadrant
Your instructor
Andy Coombs
Andy Coombs
Andy Coombs is an Advanced Practitioner in Physiotherapy with over 15 years’ experience specialising in muscul...

Episode summary

When cervical radiculopathy needs onward referral, how a Pancoast tumor presents as shoulder pain with medial plexopathy and Horner syndrome, and how to recognize arterial and venous thoracic outlet pathology and upper limb DVT.

Radiculopathy usually comes from foraminal stenosis or disc herniation, but tumors, infection, trauma, vascular and rheumatological causes can mimic it. Andy describes a C7 radiculopathy that slowly worsened despite good care and turned out to be a schwannoma. He refers when pain is severe, motor loss is marked or spans more than one nerve root, or a milder case fails to respond to conservative care. A Pancoast tumor of the lung apex makes up about 3 to 5% of lung cancers, and 96% present first with shoulder pain. Other features are C8 to T2 plexopathy symptoms, hoarseness and Horner syndrome, seen in about 25%, with ptosis, miosis and anhidrosis on one side. Smoking accounts for 71% of lung cancer. Arterial thoracic outlet syndrome, often linked to a cervical rib, causes claudication-type arm pain with coldness and pallor. Venous compression causes a hot, swollen, bluish arm with dilated superficial veins. Primary upper limb DVT, or Paget-Schroetter syndrome, affects young active people and can progress rapidly.
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