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How knee osteoarthritis is defined and staged, why it is more than wear and tear, and what the evidence says about age, obesity, previous ACL and meniscal injury, and sports participation as risk factors.
Whether running causes knee osteoarthritis, how joint loading, gait changes and muscle co-contraction relate to progression, and how to assess the knee clinically, including imaging and central sensitization.
Why exercise, weight management and education are the first-line treatment for every person with knee osteoarthritis, which types of exercise have evidence, and how to explain pain and load to patients.
How much weight loss helps people with knee osteoarthritis, and what the evidence shows for manual therapy, electrophysical modalities, glucosamine and chondroitin, and corticosteroid, hyaluronic acid and platelet-rich plasma injections.
Why arthroscopic partial meniscectomy is not recommended for degenerative knee disease, when knee replacement is considered, which factors predict persistent pain after it, and the key messages for managing knee osteoarthritis.
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